Article
Dilated cardiomyopathy is associated with reduced expression of the cardiac sodium channel Scn5a.
Cardiovascular research - 1 Aug 2007
Hesse Michael, Kondo Colleen S, Clark Robert B, Su Lin, Allen Frances L, Geary-Joo Colleen T M, Kunnathu Stanley, Severson David L, Nygren Anders, Giles Wayne R, Cross James C
Abstract excerpt
OBJECTIVE: Dilated cardiomyopathy (DCM) leads to dilation of the cardiac chambers and congestive heart failure. Recent reports have associated mutations in the SCN5A gene, which codes for the major cardiac sodium channel Nav1.5, with DCM. Although DCM is the most common form of cardiomyopathy, no...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
