Article
Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2007
Verma Ranjana, Cutler David J, Holmans Peter, Knowles James A, Crowe Raymond R, Scheftner William A, Weissman Myrna M, DePaulo J Raymond, Levinson Douglas F, Potash James B
Abstract excerpt
Recent evidence suggests a potential role for the p11 gene in conferring risk to depressive disorders. p11 has been shown to influence serotonergic transmission, and its expression was found to be reduced in a mouse model of depression, as well as in post-mortem brain tissue from major depressive...
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