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Article

Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2007

Verma Ranjana, Cutler David J, Holmans Peter, Knowles James A, Crowe Raymond R, Scheftner William A, Weissman Myrna M, DePaulo J Raymond, Levinson Douglas F, Potash James B

Abstract excerpt

Recent evidence suggests a potential role for the p11 gene in conferring risk to depressive disorders. p11 has been shown to influence serotonergic transmission, and its expression was found to be reduced in a mouse model of depression, as well as in post-mortem brain tissue from major depressive disorder (MDD) cases. In the present study, we tested for rare variants in p11 by resequencing promoter, exonic and...

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PMID: 17510952
DOI: 10.1002/ajmg.b.30514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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