Article
Mitochondrial genetic background modifies breast cancer risk.
Cancer research - 15 May 2007
Bai Ren-Kui, Leal Suzanne M, Covarrubias Daniel, Liu Aiyi, Wong Lee-Jun C
Abstract excerpt
Inefficient mitochondrial electron transport chain (ETC) function has been implicated in the vicious cycle of reactive oxygen species (ROS) production that may predispose an individual to late onset diseases, such as diabetes, hypertension, and cancer. Mitochondrial DNA (mtDNA) variations may aff...
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