Article
Genetic susceptibility to breast cancer.
Reviews in endocrine & metabolic disorders - 1 Sept 2007
Bradbury Angela R, Olopade Olufunmilayo I
Abstract excerpt
Deleterious mutations in two breast and ovarian cancer susceptibility genes, BRCA1 and BRCA2 have been identified in breast and ovarian cancer families. Women with a BRCA1 or BRCA2 mutation are candidates for additional risk reduction measures such as intensive screening, prophylactic surgery or chemoprevention. Additional susceptibility genes have been identified, including PTEN, ATM, TP53, CHEK2, CASP8, PBRL...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
