Article
Stability and robustness of an organelle number control system: modeling and measuring homeostatic regulation of centriole abundance.
Biophysical journal - 1 Sept 2007
Marshall Wallace F
Abstract excerpt
Control of organelle abundance is a fundamental unsolved problem in cell biology. Mechanisms for number control have been proposed in which organelle assembly is actively increased or decreased to compensate for deviations from a set-point, but such phenomena have not been experimentally verified. In this report we examine the control of centriole copy number. We develop a simple scheme to represent organelle...
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