Article

The one-message-per-cell-cycle rule: A conserved minimum transcription level for essential genes

2023-07-07

Abstract excerpt

The inherent stochasticity of cellular processes leads to significant cell-to-cell variation in protein abundance. Although this noise has already been characterized and modeled, its broader implications and significance remain unclear. In this paper, we revisit the noise model and identify the number of messages transcribed per cell cycle as the critical determinant of noise. In yeast, we demonstrate that this qu...

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Literature Corpus work: 6215530d-580e-59bb-b6e7-61009b3770a9
DOI: 10.1101/2023.07.06.548020

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