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Article

Sex-specific effects of ACE I/D and AGT-M235T on pulse pressure: the HyperGEN Study.

Human genetics - 1 Aug 2007

Lynch Amy I, Arnett Donna K, Pankow James S, Miller Michael B, North Kari E, Eckfeldt John H, Hunt Steven C, Rao Dabeeru C, Djoussé Luc

Abstract excerpt

Evidence shows that an elevated pulse pressure (PP) may lead to an increased risk of cardiovascular morbidity and mortality. There is also evidence that PP is a sexually dimorphic trait, and that genetic factors influence inter-individual variation in PP. The aim of this project was to assess the genotype-by-sex interaction on PP in a sample of mostly hypertensive African American and White participants using...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17492314
DOI: 10.1007/s00439-007-0370-y

Genes

ACE
AGT
DBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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