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Article

Quantitative approach to single-nucleotide polymorphism analysis using MALDI-TOF mass spectrometry.

BioTechniques - 1 Sept 2000

Ross P, Hall L, Haff L A

Abstract excerpt

Pooling of DNA samples before genotyping is a valuable means of streamlining large-scale genotyping efforts in disease association studies, single-nucleotide polymorphism (SNP) validation or mutant allele screening programs. In this report, we explore the application of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to quantitative analysis of SNPs. The measurements...

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PMID: 10997276
DOI: 10.2144/00293rr05

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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