Article
Single-nucleotide polymorphism analysis by MALDI-TOF mass spectrometry.
Trends in biotechnology - 1 Feb 2000
Griffin T J, Smith L M
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) have great potential for use in genetic-mapping studies, which locate and characterize genes that are important in human disease and biological function. For SNPs to realize their full potential in genetic analysis, thousands of different SNP loci must be screened in a rapid, accurate and cost-effective manner. Matrix-assisted laser desorption-ionization-time-of-flight...
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