Article
Risk for hepatocellular carcinoma with respect to hepatitis B virus genotypes B/C, specific mutations of enhancer II/core promoter/precore regions and HBV DNA levels.
Gut - 1 Jan 2008
Yuen M-F, Tanaka Y, Shinkai N, Poon R T, But D Yiu-Kuen, Fong D Y-T, Fung J, Wong D Ka-Ho, Yuen J Chi-Hang, Mizokami M, Lai C-L
Abstract excerpt
BACKGROUND/AIM: To examine the risks for hepatocellular carcinoma (HCC) with respect to hepatitis B virus (HBV) genotypes, specific viral mutations (MT), serum HBV DNA levels, and cirrhosis. METHODS: HBV genotypes, 1653/1753/core promoter (CP)/precore MT and HBV DNA levels were determined in 248 HBV patients with HCC and 248 HBV controls. RESULTS: Genotype C, CP-MT, T1653, HBV DNA levels >or=4 log(10) copies/ml...
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