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Article

Gene-environment interactions in geriatric depression.

The Psychiatric clinics of North America - 1 Jun 2011

Lotrich Francis E

Abstract excerpt

In older adults, several environmental challenges can potentially trigger the onset of an episode of major depression. Vulnerability to these challenges can be influenced by genetics. There is accumulating evidence for an interaction between stress and a serotonin transporter polymorphism, though there is also heterogeneity among studies. Other relevant genes include those encoding for the neuroendocrine stress...

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Share to Depressive Disorder, Major
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

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Share to Serotonin Plasma Membrane Transport Proteins

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Share to Stress, Psychological

Source

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Identifiers

PMID: 21536163
DOI: 10.1016/j.psc.2011.02.003
PMCID: PMC3087149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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