Article
Transcription of the human cell cycle regulated BUB1B gene requires hStaf/ZNF143.
Nucleic acids research - 1 Jan 2007
Myslinski Evelyne, Gérard Marie-Aline, Krol Alain, Carbon Philippe
Abstract excerpt
BubR1 is a key protein mediating spindle checkpoint activation. Loss of this checkpoint control results in chromosomal instability and aneuploidy. The transcriptional regulation of the cell cycle regulated human BUB1B gene, which encodes BubR1, was investigated in this report. A minimal BUB1B gene promoter containing 464 bp upstream from the translation initiation codon was sufficient for cell cycle regulated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
