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Article

The promoter region of the human BUBR1 gene and its expression analysis in lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2002

Seike Masahiro, Gemma Akihiko, Hosoya Yoko, Hosomi Yukio, Okano Tetsuya, Kurimoto Futoshi, Uematsu Kazutsugu, Takenaka Kiyoshi, Yoshimura Akinobu, Shibuya Masahiko, Ui-Tei Kumiko, Kudoh Shoji

Abstract excerpt

Mitotic checkpoint impairment is present in human lung cancers with chromosomal instability (CIN). Spindle-checkpoint genes have been reported to be mutated in several human cancers, but these mutations are infrequent. Recent reports suggest that the hBUBR1 gene may play an important role in mitotic checkpoint control and in mitotic checkpoint impairment in human cancers. We analyzed the expression of hBUBR1 in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12445743
DOI: 10.1016/s0169-5002(02)00218-0

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SRY

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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