Article
Innate immunity: toll-like receptors and some more. A brief history, basic organization and relevance for the human newborn.
Neonatology - 1 Jan 2007
Fleer André, Krediet Tannette G
Abstract excerpt
The discovery of Toll-like receptors (TLRs) as essential components of the innate immune system has greatly advanced our knowledge and understanding of immune responses to infection and how these are regulated. Innate immunity in general and TLRs in particular play a crucial role in the front line of host defenses against microbes, but also are a key element in the proper functioning of the immune system at large...
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