Article
Establishment and characterization of a new human Bence Jones-type myeloma cell line, NOP-2.
International journal of hematology - 1 Apr 1991
Nagai T, Ogura M, Morishita Y, Okumura M, Kato Y, Morishima Y, Hirabayashi N, Ohno R, Saito H
Abstract excerpt
A new human myeloma cell line NOP-2, producing immunoglobulin (Ig)-lambda-light chain was established from a patient with Bence Jones-type multiple myeloma. Morphologically, the cell line had plasmacytoid characteristics by light- and electron-microscopic examination. Phenotypic studies of NOP-2...
Topics
- Antigens, Neoplasm
- Bence Jones Protein
- Biomarkers, Tumor
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 22
- Chromosomes, Human, Pair 8
- Gene Rearrangement, B-Lymphocyte
- Humans
- Male
- Middle Aged
- Multiple Myeloma
- Phenotype
- RNA, Messenger
- RNA, Neoplasm
- Translocation, Genetic
- Tumor Cells, Cultured