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Article

Glutathione S-transferase M1 null genotype as a risk factor for carbamazepine-induced mild hepatotoxicity.

Pharmacogenomics - 1 May 2007

Ueda Kentaro, Ishitsu Takateru, Seo Takayuki, Ueda Nao, Murata Tsukasa, Hori Masaharu, Nakagawa Kazuko

Abstract excerpt

UNLABELLED: The aim of this study is to verify whether the combination of glutathione S-transferase (GST) M1 null and GSTT1 null genotypes, which is a candidate genetic risk factor for troglitazone-induced liver failure, is common to that for the carbamazepine-induced mild hepatotoxicity. PATIENTS & METHODS: The genotypes of GSTM1 and GSTT1, and microsomal epoxide hydrolase-3 and -4, were determined in 192...

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Source

Identifiers

PMID: 17465707
DOI: 10.2217/14622416.8.5.435

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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