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Article

Glutathione S-transferases T1 null genotype is associated with susceptibility to aristolochic acid nephropathy.

International urology and nephrology - 1 Feb 2012

Chen Bicheng, Bai Yongheng, Sun Mei, Ni Xiaojie, Yang Yunxiu, Yang Yirong, Zheng Shaoling, Xu Feifei, Dai Shengchuan

Abstract excerpt

OBJECTIVES: This study aims to determine whether six polymorphisms of the genes involved in drug metabolism are associated with susceptibility to the development and progression of aristolochic acid nephropathy (AAN). METHODS: In the study, 91 aristolochic acid nephropathy (AAN) cases and 152 healthy controls of Chinese Han population were examined. Six common polymorphisms of genes, including multidrug...

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Source

Identifiers

PMID: 22116675
DOI: 10.1007/s11255-011-0082-z

Genes

GSTT1
GSTM1
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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