Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glyoxal-induced premature senescence in human fibroblasts.

Annals of the New York Academy of Sciences - 1 Apr 2007

Sejersen Henrik, Rattan Suresh I S

Abstract excerpt

Mild stress-induced hormesis is an effective strategy to intervene in the aging process. Repeated exposure of human skin fibroblasts to 41 degrees C heat shock for 1 h twice a week is an example of mild stress that has many hormetic effects, including improved resistance to other stressors. We are now developing an experimental model system of sugar-induced premature senescence, which can be useful to test the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidants
Share to Bromodeoxyuridine
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Damage

Share to Dose-Response Relationship, Drug

Share to Fibroblasts

Share to Oxidative Stress

Source

Identifiers

PMID: 17460217
DOI: 10.1196/annals.1395.057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glyoxal-induced premature senescence in human fibroblasts.PMID 17460217Read ↗

Hormetic Prevention of Molecular Damage during Cellular Aging of Human Skin Fibroblasts and KeratinocytesSemantic proximity Read ↗

Modeling of the Senescence-Associated Phenotype in Human Skin Fibroblasts.Semantic proximity Read ↗

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytesSemantic proximity Read ↗

The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype.Semantic proximity Read ↗

Dicarbonyl-induced accelerated aging in vitro in human skin fibroblasts.Semantic proximity Read ↗

Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-β1 signaling pathwaySemantic proximity Read ↗

Proteomic and phenotypic profiling of replicative-senescent human foreskin fibroblasts under brief heat shock.Semantic proximity Read ↗

Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblastSemantic proximity Read ↗

Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging.Semantic proximity Read ↗

Human dermal fibroblast senescence in response to single and recurring oxidative stressSemantic proximity Read ↗

Modulation of PPARγ Provides New Insights in a Stress Induced Premature Senescence ModelSemantic proximity Read ↗

Low-energy green light alleviates senescence-like phenotypes in a cell model of photoaging.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.