Article
The differentiation-associated linker histone, H1.0, during the in vitro aging and senescence of human diploid fibroblasts.
Annals of the New York Academy of Sciences - 1 Apr 2007
Sekeri-Pataryas Kalliope E, Sourlingas Thomae G
Abstract excerpt
There are numerous similarities between aging/senescence and differentiation. One key similarity is that in both biological processes chromatin remodeling events occur. It is now known that during both processes there is a reorganization of eu- and heterochromatic domains and an increase in heterochromatin, known as heterochromatinization. Previous work of more than two decades has shown that the replacement H1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.