Article
[The effect of two newly Chinese presenilin-1 mutations on the sensitivity to trophic factor withdrawal in human neuroblastoma cells].
Zhonghua yi xue za zhi - 30 Jan 2007
Fang Bo-yan, Jia Jian-ping
Abstract excerpt
OBJECTIVE: To study the effects of two novel presenilin-1 (PS1) mutations, V97L and A136G, discovered in 2 families of Alzheimer's disease (AD) in China, on human neuroblastoma cells and the protective role of insulin-like growth factor-1 (IGF-1). METHODS: Two mutation type (MT) PS-1 genes with t...
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