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[Study on the mechanism of Alzheimer disease-related gene presenilin-1].

Zhonghua nei ke za zhi - 1 Aug 2003

Peng Dan-tao, Xu Xian-hao, Feng Ying, Peng Le

Abstract excerpt

OBJECTIVE: To study the pathogenic mechanism of Alzheimer disease-related gene presenilin-1 (PS-1) mutation causing AD. METHODS: Four neural cells, including SY5Y cell, transgenic cells harboring PS-1 mutation, wild-type PS-1 and lipofectin were measured for neuronal Ca(2+) homeostasis and cell apoptosis. Intracellular calcium antagonist and antioxidant, such as Ginaton and nimodipine, were used in cultured...

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PMID: 14505542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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