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Article

Lack of association between genetic polymorphisms in cytokine genes and disease expression in patients with hereditary non-polyposis colorectal cancer.

Scandinavian journal of gastroenterology - 1 May 2007

Talseth Bente A, Meldrum Cliff, Suchy Janina, Kurzawski Grzegroz, Lubinski Jan, Scott Rodney J

Abstract excerpt

OBJECTIVE: Hereditary non-polyposis colorectal cancer (HNPCC) is caused by germline mutations in DNA mismatch repair (MMR) genes and is characterized by familial aggregations of early-onset epithelial cancers. Inflammatory cells produce an attractive environment for tumour growth since reactive oxygen and nitrogen species generated by inflammatory cytokine induction can cause damage to DNA and proteins. In this...

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PMID: 17454884
DOI: 10.1080/00365520601106699

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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