Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Risk and protective haplotypes of the alpha-synuclein gene associated with Parkinson's disease differentially affect cognitive sequence learning.

Genes, brain, and behavior - 1 Feb 2008

Kéri S, Nagy H, Myers C E, Benedek G, Shohamy D, Gluck M A

Abstract excerpt

Alpha-synuclein (SNCA) is a key factor in the regulation of dopaminergic transmission and is related to Parkinson's disease. In this study, we investigated the effects of risk and protective SNCA haplotypes associated with Parkinson's disease on cognitive sequence learning in 204 healthy volunteers. We found that the 3'-block risk SNCA haplotypes are associated with less effective stimulus-reward learning of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Association Learning
Share to Attention

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Basal Ganglia

Share to Color Perception

Share to Mental Recall

Share to Motivation

Share to Psychomotor Performance

Share to Temporal Lobe

Source

Identifiers

PMID: 17451452
DOI: 10.1111/j.1601-183X.2007.00315.x

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk and protective haplotypes of the alpha-synuclein gene associated with Parkinson's disease differentially affect cognitive sequence learning.PMID 17451452Read ↗

The role of dopamine in cognitive sequence learning: evidence from Parkinson’s diseaseSemantic proximity Read ↗

Aging and a genetic KIBRA polymorphism interactively affect feedback- and observation-based probabilistic classification learning.Semantic proximity Read ↗

Effects of aging and dopamine genotypes on the emergence of explicit memory during sequence learning.Semantic proximity Read ↗

α-Synuclein gene duplication impairs reward learningSemantic proximity Read ↗

Motor sequence learning deficits in idiopathic Parkinson’s disease are associated with increased substantia nigra activitySemantic proximity Read ↗

Dopaminergic genes predict individual differences in susceptibility to confirmation bias.Semantic proximity Read ↗

DAT1 polymorphism determines L-DOPA effects on learning about others' prosociality.Semantic proximity Read ↗

Effects of dopamine on reinforcement learning in Parkinson's disease depend on motor phenotype.Semantic proximity Read ↗

Commonly-occurring polymorphisms in the COMT, DRD1 and DRD2 genes influence different aspects of motor sequence learning in humans.Semantic proximity Read ↗

Striatal dopamine mediates the interface between motivational and cognitive control in humans: evidence from genetic imaging.Semantic proximity Read ↗

Task-dependent interactions between dopamine D2 receptor polymorphisms and L-DOPA in patients with Parkinson's disease.Semantic proximity Read ↗

alpha-Synuclein gene haplotypes are associated with Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.