Article
Neuregulin-1 genotype moderates the association between job strain and early atherosclerosis in young men.
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine - 1 Apr 2007
Hintsanen Mirka, Elovainio Marko, Puttonen Sampsa, Kivimäki Mika, Raitakari Olli T, Lehtimäki Terho, Rontu Riika, Juonala Markus, Kähönen Mika, Viikari Jorma, Keltikangas-Järvinen Liisa
Abstract excerpt
BACKGROUND: Although it is known that a given level of strain does not induce a corresponding CHD risk in all individuals, factors that predict groups at risk have remained unclear. Neuregulin-1 (NRG-1) has various roles in the development and function of the heart and autonomic nervous system. PURPOSE: We examined whether polymorphic variation in NRG-1 moderates the association between job strain and early...
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