Mutations affecting the biogenesis of the AIDA-I autotransporter.

Abstract excerpt

Autotransporters are simple systems that Gram-negative bacteria employ to secrete proteins to their surfaces or into the extracellular milieu. They consist of an N-terminal passenger domain and a C-terminal domain that is thought to insert into the outer membrane and mediate the secretion of the passenger domain. Despite the apparent simplicity of these secretion systems, their mechanism of translocation is still...

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