Article
Tumor necrosis factor alpha -238G>A genotype alters postprandial plasma levels of free fatty acids in obese individuals with type 2 diabetes mellitus.
Metabolism: clinical and experimental - 1 May 2007
Fontaine-Bisson Bénédicte, Wolever Thomas M S, Chiasson Jean-Louis, Rabasa-Lhoret Rémi, Maheux Pierre, Josse Robert G, Leiter Lawrence A, Rodger N Wilson, Ryan Edmond A, El-Sohemy Ahmed
Abstract excerpt
Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine that impairs insulin action and alters lipid metabolism. We investigated the effects of genetic polymorphisms of TNF-alpha on circulating biomarkers of insulin resistance and lipid metabolism during an 8-hour metabolic profile...
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