Article
Venlafaxine exhibits an anti-inflammatory effect in an inflammatory co-culture model.
The international journal of neuropsychopharmacology - 1 Feb 2008
Vollmar Patrick, Haghikia Aiden, Dermietzel Rolf, Faustmann Pedro M
Abstract excerpt
Growing evidence indicates immunoregulatory effects of various antidepressants. Through the interaction of the nervous and immune systems, the norepinephrine-serotonin system was shown to modulate inflammatory CNS diseases. Thus, we examined the norepinephrine-serotonin reuptake inhibitor venlafaxine in an astroglia-microglia co-culture model which allows mimicking of an inflammatory milieu by increasing the...
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