Recurrent spontaneous abortions patients have more −14 bp/+14 bp heterozygotes in the 3′UT region of the HLA‐G gene in a Chinese Han population

Abstract excerpt

Although human leukocyte antigen (HLA)-G gene polymorphism is low, it may influence levels of protein expression and, in some cases, has been associated with pregnancy diseases. Apart from the 23 HLA-G alleles, including a null allele known as HLA-G*0105N, a 14-bp deletion or insertion in the 3'UT region also contributes to the HLA-G gene polymorphism. In order to discover any correlation between the 14-bp...

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