Article
Cytotoxicity of lawsone and cytoprotective activity of antioxidants in catalase mutant Escherichia coli.
Toxicology - 3 Jun 2007
Sauriasari Rani, Wang Da-Hong, Takemura Yoko, Tsutsui Ken, Masuoka Noriyoshi, Sano Kuniaki, Horita Masako, Wang Bing-Ling, Ogino Keiki
Abstract excerpt
Lawsone is an active naphthoquinone derivative isolated from henna (Lawsonia inermis L.), a widely used hair dye. Previous study on the toxicity of lawsone remains unclear since the involvement of oxidative stress and the kind of ROS (reactive oxygen species) involved have not been fully resolved yet. This present study reports the cytotoxic effects of lawsone and henna. We carried out CAT assay (a zone of...
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