Article
Involvement of oxidative stress in hydroquinone-induced cytotoxicity in catalase-deficient Escherichia coli mutants.
Free radical research - 1 Oct 2005
Horita Masako, Wang Da-Hong, Tsutsui Ken, Sano Kuniaki, Masuoka Noriyoshi, Kira Shohei
Abstract excerpt
Hydroquinone is a benzene-derived metabolite. To clarify whether the reactive oxygen species (ROS) are involved in hydroquinone-induced cytotoxicity, we constructed transformants of Escherichia coli (E. coli) strains that express mammalian catalase gene derived from catalase mutant mice (Cs(b), Cs(c)) and the wild-type (Cs(a)) using a catalase-deficient E. coli UM255 as a recipient. Specific catalase activities...
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