Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities.

doi:10.1093/mutage/gem016

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Article

Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities.

Mutagenesis - 1 Jul 2007

Moura Dinara Jaqueline, Richter Marc François, Boeira Jane Marlei, Pêgas Henriques João Antonio, Saffi Jenifer

Abstract excerpt

The beta-carboline alkaloids found in medical plants and in a variety of foods, beverages and cigarette smoke have a range of action in various biological systems. In vitro studies have demonstrated that these alkaloids can act as scavengers of reactive oxygen species. In this paper, we report the in vivo antioxidative properties of the aromatic (harmane, harmine, harmol) and dihydro-beta-carbolines (harmaline...

Topics

Alkaloids
Animals
Antimutagenic Agents
Antioxidants
Carbolines
Cell Line
Comet Assay
Cricetinae
Cricetulus
Genes, Fungal
Hydrogen Peroxide
Mutation
Saccharomyces cerevisiae

Source

Open in PubMed

Identifiers

PMID: 17545209
DOI: 10.1093/mutage/gem016

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