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Article

Abnormal folate metabolism in foetuses affected by neural tube defects.

Brain : a journal of neurology - 1 Apr 2007

Dunlevy Louisa P E, Chitty Lyn S, Burren Katie A, Doudney Kit, Stojilkovic-Mikic Taita, Stanier Philip, Scott Rosemary, Copp Andrew J, Greene Nicholas D E

Abstract excerpt

Folic acid supplementation can prevent many cases of neural tube defects (NTDs), whereas suboptimal maternal folate status is a risk factor, suggesting that folate metabolism is a key determinant of susceptibility to NTDs. Despite extensive genetic analysis of folate cycle enzymes, and quantifica...

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Identifiers

PMID: 17438019
DOI: 10.1093/brain/awm028
PMCID: PMC7614420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17438019-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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