Article
GLOGS: a fast and powerful method for GWAS of binary traits with risk covariates in related populations.
Bioinformatics (Oxford, England) - 1 Jun 2012
Stanhope Stephen A, Abney Mark
Abstract excerpt
SUMMARY: Mixed model-based approaches to genome-wide association studies (GWAS) of binary traits in related individuals can account for non-genetic risk factors in an integrated manner. However, they are technically challenging. GLOGS (Genome-wide LOGistic mixed model/Score test) addresses such challenges with efficient statistical procedures and a parallel implementation. GLOGS has high power relative to...
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