Identification of a unique specificity determinant of the colicin E3 immunity protein.

doi:10.1016/0378-1119(91)90306-v

Back to search

Article

Identification of a unique specificity determinant of the colicin E3 immunity protein.

Gene - 30 Oct 1991

Masaki H, Akutsu A, Uozumi T, Ohta T

Abstract excerpt

Plasmid immunity to a nuclease-type colicin is defined by the specific binding of an immunity (or inhibitor) protein, Imm, to the C-terminal nuclease domain, T2A, of the colicin molecule. Whereas most regions of colicin operons exhibit extensive sequence identity, the small plasmid region encodin...

Topics

Amino Acid Sequence
Bacterial Proteins
Base Sequence
Cloning, Molecular
Colicins
DNA Mutational Analysis
Escherichia coli
Escherichia coli Proteins
Genes, Lethal
Molecular Sequence Data
Mutation
Operon
Plasmids
SOS Response, Genetics
Sequence Homology, Nucleic Acid

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.