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Article

Engineering resistance to phage GVE3 in Geobacillus thermoglucosidasius.

Applied microbiology and biotechnology - 1 Feb 2016

van Zyl Leonardo Joaquim, Taylor Mark Paul, Trindade Marla

Abstract excerpt

Geobacillus thermoglucosidasius is a promising platform organism for the production of biofuels and other metabolites of interest. G. thermoglucosidasius fermentations could be subject to bacteriophage-related failure and financial loss. We develop two strains resistant to a recently described G. thermoglucosidasius-infecting phage GVE3. The phage-encoded immunity gene, imm, was overexpressed in the host leading...

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PMID: 26536875
DOI: 10.1007/s00253-015-7109-9

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