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Article

A dual lethal system to enhance containment of recombinant micro-organisms.

Microbiology (Reading, England) - 1 Dec 2003

Torres Begoña, Jaenecke Susanne, Timmis Kenneth N, García José L, Díaz Eduardo

Abstract excerpt

Active containment systems based on the controlled expression of a lethal gene are designed to increase containment of recombinant micro-organisms used for environmental applications. A major drawback in containment is the existence of mutations that generate surviving cells that cease to respond to the toxic effect of the lethal function. In this work the authors have developed for the first time a strategy to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14663091
DOI: 10.1099/mic.0.26618-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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