Article
Deletion of the cruciform binding domain in CBP/14-3-3 displays reduced origin binding and initiation of DNA replication in budding yeast.
BMC molecular biology - 12 Apr 2007
Yahyaoui Wafaa, Callejo Mario, Price Gerald B, Zannis-Hadjopoulos Maria
Abstract excerpt
BACKGROUND: Initiation of eukaryotic DNA replication involves many protein-protein and protein-DNA interactions. We have previously shown that 14-3-3 proteins bind cruciform DNA and associate with mammalian and yeast replication origins in a cell cycle dependent manner. RESULTS: By expressing the...
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