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Article

PCR-restriction fragment length polymorphism for rapid, low-cost identification of isoniazid-resistant Mycobacterium tuberculosis.

Journal of clinical microbiology - 1 Jun 2007

Caws Maxine, Tho Dau Quang, Duy Phan Minh, Lan Nguyen Thi Ngoc, Hoa Dai Viet, Torok Mili Estee, Chau Tran Thi Hong, Chau Nguyen Van Vinh, Chinh Nguyen Tran, Farrar Jeremy

Abstract excerpt

PCR-restriction fragment length poymorphism (PCR-RFLP) is a simple, robust technique for the rapid identification of isoniazid-resistant Mycobacterium tuberculosis. One hundred consecutive isolates from a Vietnamese tuberculosis hospital were tested by MspA1I PCR-RFLP for the detection of isoniazid-resistant katG_315 mutants. The test had a sensitivity of 80% and a specificity of 100% against conventional...

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Identifiers

PMID: 17428939
DOI: 10.1128/JCM.01960-06
PMCID: PMC1933100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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