Article
Foxp2 and Foxp1 cooperatively regulate lung and esophagus development.
Development (Cambridge, England) - 1 May 2007
Shu Weiguo, Lu Min Min, Zhang Yuzhen, Tucker Philip W, Zhou Deying, Morrisey Edward E
Abstract excerpt
The airways of the lung develop through a reiterative process of branching morphogenesis that gives rise to the intricate and extensive surface area required for postnatal respiration. The forkhead transcription factors Foxp2 and Foxp1 are expressed in multiple foregut-derived tissues including the lung and intestine. In this report, we show that loss of Foxp2 in mouse leads to defective postnatal lung...
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