Article
Foxp2 regulates anatomical features that may be relevant for vocal behaviors and bipedal locomotion.
Proceedings of the National Academy of Sciences of the United States of America - 28 Aug 2018
Xu Shuqin, Liu Pei, Chen Yuanxing, Chen Yi, Zhang Wei, Zhao Haixia, Cao Yiwei, Wang Fuhua, Jiang Nana, Lin Shifeng, Li Baojie, Zhang Zhenlin, Wei Zhanying, Fan Ying, Jin Yunyun, He Lin, Zhou Rujiang, Dekker Joseph D, Tucker Haley O, Fisher Simon E, Yao Zhengju, Liu Quansheng, Xia Xuechun, Guo Xizhi
Abstract excerpt
Fundamental human traits, such as language and bipedalism, are associated with a range of anatomical adaptations in craniofacial shaping and skeletal remodeling. However, it is unclear how such morphological features arose during hominin evolution. FOXP2 is a brain-expressed transcription factor implicated in a rare disorder involving speech apraxia and language impairments. Analysis of its evolutionary history...
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