Article
Distinct transcriptional profiles characterize oral epithelium-microbiota interactions.
Cellular microbiology - 1 Jun 2005
Handfield Martin, Mans Jeffrey J, Zheng Gaolin, Lopez M Cecilia, Mao Song, Progulske-Fox Ann, Narasimhan Giri, Baker Henry V, Lamont Richard J
Abstract excerpt
Transcriptional profiling, bioinformatics, statistical and ontology tools were used to uncover and dissect genes and pathways of human gingival epithelial cells that are modulated upon interaction with the periodontal pathogens Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. Consistent with their biological and clinical differences, the common core transcriptional response of epithelial cells...
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