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Article

[The influence of CYP2C9 genetic polymorphism on the pharmacokinetics and pharmacodynamics of warfarin in patients with constant atrial fibrillation].

Klinicheskaia meditsina - 1 Jan 2007

Sychev D A, Mikheeva Iu A, Kropacheva E S, Ignat'ev I V, Bulytova Iu M, Ramenskaia G V, Dobrovol'skiĭ A B, Panchenko E P, Kukes V G

Abstract excerpt

CYP2C9 is the main enzyme participating in warfarin metabolism, of which genetic polymorphism is typical. The aim of the study was to investigate the influence of having allelic variants CYP2C9*2 and CYP2C9*3 on the pharmacokinetics, dosage regimen, and the rate of hemorrhage in patients with con...

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PMID: 17419358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17419358-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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