Article
Prefrontal cognition in schizophrenia and bipolar illness in relation to Val66Met polymorphism of the brain-derived neurotrophic factor gene.
Psychiatry and clinical neurosciences - 1 Feb 2006
Rybakowski Janusz K, Borkowska Alina, Skibinska Maria, Szczepankiewicz Aleksandra, Kapelski Pawel, Leszczynska-Rodziewicz Anna, Czerski Piotr M, Hauser Joanna
Abstract excerpt
The measures of prefrontal cognition have been used as endophenotype in molecular-genetic studies. Brain-derived neurotrophic factor (BDNF) has been implicated in cognitive functions and in the pathogenesis of major psychoses. This study investigates the relationship between Val66Met polymorphisms of the BDNF gene and prefrontal cognitive function in 129 patients with schizophrenia and 111 patients with bipolar...
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