Article
An association study of dopamine receptors polymorphisms and the Wisconsin Card Sorting Test in schizophrenia.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2005
Rybakowski J K, Borkowska A, Czerski P M, Kapelski P, Dmitrzak-Weglarz M, Hauser J
Abstract excerpt
Dopamine (DA), an important neurotransmitter in prefrontal cortex (PFC), is involved in the pathogenesis of schizophrenia. The aim of the study was to test an association between common polymorphism of genes for DA receptors DRD1, DRD2, DRD3, DRD4, and performance on the Wisconsin Card Sorting Test (WCST), measuring various functions of PFC, in 138 schizophrenic patients. Patients with G/G genotype of DRD1 tended...
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