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BRCA1/2 mutation screening in high-risk breast/ovarian cancer families and sporadic cancer patient surveilling for hidden high-risk families.

BMC medical genetics - 14 Jun 2013

Berzina Dace, Nakazawa-Miklasevica Miki, Zestkova Jekaterina, Aksenoka Karina, Irmejs Arvids, Gardovskis Andris, Kalniete Dagnija, Gardovskis Janis, Miklasevics Edvins

Abstract excerpt

BACKGROUND: The estimated ratio of hereditary breast/ovarian cancer (HBOC) based on family history is 1.5% in Latvia. This is significantly lower than the European average of 5-10%. Molecular markers like mutations and SNPs can help distinguish HBOC patients in the sporadic breast and ovarian cancer group. METHODS: 50 patients diagnosed with HBOC in the Latvian Cancer Registry from January 2005 to December 2008...

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Identifiers

PMID: 23767878
DOI: 10.1186/1471-2350-14-61
PMCID: PMC3686592

Genes

BRCA2
BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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