Article
Analysis of the influence of two CD24 genetic variants in Crohn's disease and ulcerative colitis.
Human immunology - 1 Oct 2011
Diaz-Gallo Lina-Marcela, Medrano Luz María, Gómez-García María, Cardeña Carlos, Rodrigo Luis, Mendoza Juan Luis, Taxonera Carlos, Nieto Antonio, Alcain Guillermo, Cueto Ignacio, López-Nevot Miguel A, Urcelay Elena, Martin Javier
Abstract excerpt
The aim of this study was to evaluate the possible implication of CD24 gene in the genetic predisposition to inflammatory bowel disease (IBD). Our study population consisted of 1321 female Spanish individuals (369 Crohn's disease [CD] patients, 323 ulcerative colitis [UC] patients, and 629 healthy matched controls). Two putative functional polymorphisms, a C to T coding polymorphism (rs8734) and a TG deletion in...
Topics
- Adolescent
- Adult
- Alleles
- CD24 Antigen
- Case-Control Studies
- Colitis, Ulcerative
- Crohn Disease
- Female
- Gene Frequency
- Genetic Predisposition to Disease