Yeast RAD14 and human xeroderma pigmentosum group A DNA-repair genes encode homologous proteins.

doi:10.1038/355555a0

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Article

Yeast RAD14 and human xeroderma pigmentosum group A DNA-repair genes encode homologous proteins.

Nature - 6 Feb 1992

Bankmann M, Prakash L, Prakash S

Abstract excerpt

Xeroderma pigmentosum (XP), a human autosomal recessive disorder, is characterized by extreme sensitivity to sunlight and high incidence of skin cancers. XP cells are defective in the incision step of excision repair of DNA damaged by ultraviolet light. Cell fusion studies have defined seven XP complementation groups, XP-A to XP-G. Similar genetic complexity of excision repair is observed in the yeast...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
DNA
DNA Repair
DNA Repair Enzymes
Dose-Response Relationship, Radiation
Fungal Proteins
Humans
Mice
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis, Insertional

Mutation

Plasmids

Restriction Mapping

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

Open in PubMed

Identifiers

PMID: 1741034
DOI: 10.1038/355555a0

Genes

RAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1741034-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Yeast RAD14 and human xeroderma pigmentosum group A DNA-repair genes encode homologous proteins.PMID 1741034Read ↗

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