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Article

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint.

The EMBO journal - 28 Jan 2004

Giannattasio Michele, Lazzaro Federico, Longhese Maria Pia, Plevani Paolo, Muzi-Falconi Marco

Abstract excerpt

The mechanisms used by checkpoints to identify DNA lesions are poorly understood and may involve the function of repair proteins. Looking for mutants specifically defective in activating the checkpoint following UV lesions, but proficient in the response to methyl methane sulfonate and double-strand breaks, we isolated cdu1-1, which is allelic to RAD14, the homolog of human XPA, involved in lesion recognition...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14726955
DOI: 10.1038/sj.emboj.7600051
PMCID: PMC1271758

Genes

XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dissecting the DNA damage response : structural and biochemical insights into the Mec1-Ddc2 checkpoint kinase complexSemantic proximity Read ↗

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