Article
MetaNetwork: a computational protocol for the genetic study of metabolic networks.
Nature protocols - 1 Jan 2007
Fu Jingyuan, Swertz Morris A, Keurentjes Joost J B, Jansen Ritsert C
Abstract excerpt
We here describe the MetaNetwork protocol to reconstruct metabolic networks using metabolite abundance data from segregating populations. MetaNetwork maps metabolite quantitative trait loci (mQTLs) underlying variation in metabolite abundance in individuals of a segregating population using a two-part model to account for the often observed spike in the distribution of metabolite abundance data. MetaNetwork...
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