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Article

Symmetrical localization of extrachromosomally replicating viral genomes on sister chromatids

4 Apr 2007

Abstract excerpt

In eukaryotes, many latent viruses replicate as extrachromosomal molecules, called episomes, and efficiently segregate to daughter cells by noncovalently attaching to mitotic chromosomes. To understand the mechanism governing the processes, we analyzed the detailed subcellular localization of Epstein-Barr virus (EBV) genomes and a viral protein EBNA1, a bridging molecule between viral genomes and cellular...

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PMID: 17405814
DOI: 10.1242/jcs.03434

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Symmetrical localization of extrachromosomally replicating viral genomes on sister chromatidsPMID 17405814Read ↗

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